|
These publications are in PDF format.
To view PDF files, get Adobe Acrobat Reader 
 Hammoud, S., Nix, D., Zhang, H., Purwar, J., Carrell, D., Cairns, B. Distinctive chromatin in human sperm packages genes for embryo development (2009) Nature, [epub ahead of print]
Cedric R. Clapier and B.R. Cairns (2009) The Biology of Chromatin Remodeling Complexes. Annual Review of Biochemistry Vol. 78: 273-304 [epub ahead of print]
Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45 Cell 2008 Dec 26; 13 (7):1201-12.
Data
Dutrow, N., Nix, D., Holt, D., Milash, B., Dalley, B., Westbroek, E., Parnell, T., and Cairns, B.R. Dynamic Transcriptome of Schizosaccharomyces pombe shown by RNA-DNA hybrid mapping. Nature Genetics 2008; 40(8), 977-986.
Szerlong, H., Hinata, K., Viswanathan, R., Erdjument-Bromage, H., Tempst, P., and Cairns B.R. The HSA domain binds actin-related proteins to regulate chromatin remodeling ATPases. Nature Str. & Mol. Biol. 2008; 15(5), 469-476.
Parnell, T., Huff, J.T., and Cairns, B.R. (2007) RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes. EMBO Journal (Dec. 6, 2007 Epub)
Fischer, C. Saha, A., and Cairns B. R. (2007) Kinetic Model for the ATP-dependent Translocation of S. cerevisiae RSC along double-stranded DNA. Biochemistry 46(43):12416-26.
VanDemark, A.P., Kasten M.M., Ferris, E., Heroux, A., Hill, C.P., and Cairns B.R. (2007) Autoregulation of the Rsc4 Tandem Bromodomain by Gcn5 Acetylation. Molecular Cell, 27(5):817-28.
Gordon, M., Holt, D., Panigrahi, A., Wilhelm, B.T., Erdjument-Bromage, H., Tempst, P., Bähler, J., and Cairns B. R. (2007) Genome-wide dynamics of SAPHIRE, an essential complex for gene activation and chromatin boundaries. Molecular and Cellular Biology 27(11), 4058-69.
Leschziner A.E., Saha, A. , Wittmeyer, J., Zhang, Y., Bustamante, C., Cairns, B.R., and Nogales, E. (2007) Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method. PNAS 104(12):4913-8.
Rai, K., S., Chidester, S., Svala C.V., Manos, E.J., James, S.R., Karpf, A.R., Jones, D.A. and Cairns, B.R. (2007) Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes & Dev. 21(3), 261-266.
Zhang Y. , Smith, C.L. , Saha, A., Grill, S.W. , Mihardja, S., Smith S. B. , Cairns B. R., Peterson C. L. , and Bustamante C. (2006) DNA Translocation and Loop Formation Mechanism of Chromatin Remodeling by SWI/SNF and RSC. Molecular Cell 24, 559-568.
Rai, K., Nadauld, L.D., Chidester S., Manos, E.J., James S.R., Karpf, A.R., Cairns, B.R., and Jones, D.A. (2006) Zebrafish dnmt1 and suv39h1 have overlapping and organ-specific functions in zebrafish development. Molecular and Cellular Biology, 26; 7077-7085
Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Pena P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Cote J, Chua KF, and Gozani O. (2006) ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature. Jul 6;442(7098):96-9.
Bordas-Le Floch, V., Gendrel, G., Soutorina, J., Flores, A, Dumay-Odelot H., Soularue, P., Navarro, F., Cairns, B.R., Lefebvre, O., and Werner, M. (2006) The Rsc4 C-terminus connects the chromatin remodeler RSC to RNA polymerases. Molecular and Cellular Biology, 26 (13), 4920-4933.
Roberts, D., Wilson, B., Huff, J., Stewart, A., and Cairns, B.R. (2006) Dephosphorylation and genome-wide association of Maf1 with Pol III genes in transcriptional repression. Molecular Cell, 22 (5) 633-644.
Da, G., Lenkart, J., Zhao, K., Shiekhattar, R., Cairns, B. R. and Marmorstein, R. (2006) Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes. Proc. Natl. Acad. Sci., 103 (7), 2057-2063.
Wilson, B., Erdjument Bromage, H., Tempst, P., and Cairns B.R. (2006) The RSC chromatin remodeling complex bears an essential yeast-specific module with broad functional roles. Genetics, 172 (2), 795-809.
Guoping
Da, Jeffrey Lenkart, Kehao Zhao, Ramin Shiekattar, Bradley R. Cairns,
and Ronen Marmorstein. (2006) Structure
and function of the SWIRM domain, a conserved protein module found in
chromatin regulatory complexes. PNAS 103(7):2057-2062.
Supplemental method and images for above
Table
3 Table
4
Schlichter,
A., and Cairns, B.R. (2005) Histone
trimethylation by Set1 is coordinated by the RRM, autoinhibitory and catalytic
domains. EMBO Journal, 24, 1222-1231.
Supplemental method and images for above
Table
S1 Figure
1 Figure
2
Chai, B., Huang, J., Cairns, B.R. and Laurent, B.C. (2005) Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-stranded break repair. Genes Dev. 19(14):1656-61.
Supplemental images for above
Figure 1
Figure 2
Figure 3
Figure 4
Saha, A., Wittmeyer, J., and Cairns, B.R. (2005) Chromatin remodeling through DNA translocation from an internal nucleosomal site. Nature Structural & Mol. Biol., 12(9):747-55.
Supplemental method and images for above
Method
Method (doc)
Figure 1
Wilson,
B., Erdjument Bromage, H., Tempst, P., and Cairns B.R. (2005) The
RSC chromatin remodeling complex bears an essential yeast-specific module
with broad functional roles. Genetics (in press)
Zhang,
H., Roberts, D., and Cairns, B.R. (2005) Genome-wide
dynamics of Htz1, a conserved histone H2A variant that poises repressed
genes for activation through histone loss. Cell
Supplemental
data, and tables
Data
Table
3 Table
4
Zhang H, Richardson DO, Roberts DN, Utley R, Erdjument-Bromage H, Tempst P, Cote J, Cairns BR
The Yaf9 component of the SWR1 and NuA4 complexes is required for
proper gene expression, histone H4 acetylation,
and Htz1 replacement near telomeres
Mol Cell Biol. 2004 Nov;24(21):9424-36
Supplemental methods, tables and images
Methods
Table 1
Microarray and ChIP Chip Data
Supplemental Images
Margaret Kasten, Heather Szerlong, Hediye Erdjument-Bromage, Paul Tempst,
Michel Werner, and Bradley R. Cairns
Tandem bromodomains in the chromatin remodeler RSC recognize
acetylated histone H3 Lys 14.
EMBO J. 2004 (23) 1348-1359
Supplemental methods and images for above
Method
Figure 1
Figure 2
Figure 3
Douglas
N. Roberts, Allen J. Stewart, Jason T. Huff, and Bradley R. Cairns
The RNA polymerase III transcriptome
revealed by genome-wide localization
and activity-occupancy relationships.
Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14695-700
Supplemental tables for above
Table 1
Table 2
Table 3
Supplemental methods and images (HTML)
Roberts Supplemental
Szerlong H, Saha A, Cairns BR.
The nuclear actin-related proteins
Arp7 and Arp9: a dimeric module that cooperates with architectural
proteins for chromatin remodeling.
EMBO J. 2003 Jun 16;22(12):3175-87.
Romeo MJ, Angus-Hill ML, Sobering AK, Kamada Y, Cairns BR, Levin DE.
HTL1 encodes a novel factor that interacts with the RSC chromatin
remodeling complex in Saccharomyces cerevisiae.
Mol Cell Biol. 2002 Dec;22(23):8165-74.
Supplemental tables for above
Table 1
Table 2
Kristjuhan A, Walker J, Suka N, Grunstein M, Roberts D,
Cairns BR, Svejstrup JQ.
Transcriptional
inhibition of genes with severe histone h3 hypoacetylation in
the coding region.
Mol Cell. 2002 Oct;10(4):925-33.
Saha A, Wittmeyer J, Cairns BR.
Chromatin remodeling by RSC involves
ATP-dependent DNA translocation.
Genes Dev. 2002 Aug 15;16(16):2120-34.
Damelin M, Simon I, Moy TI, Wilson B, Komili S, Tempst P, Roth
FP, Young RA, Cairns BR, Silver PA.
The genome-wide localization of Rsc9,
a component of the RSC chromatin-remodeling
complex, changes in response to stress.
Mol Cell. 2002 Mar;9(3):563-73.
Cairns BR.
Emerging roles for chromatin remodeling in cancer biology.
Trends Cell Biol. 2001 Nov;11(11):S15-21. Review.
Sengupta SM, VanKanegan M, Persinger J, Logie C, Cairns BR, Peterson
CL, Bartholomew B.
The interactions of yeast SWI/SNF and RSC with the nucleosome before
and after chromatin remodeling.
J Biol Chem. 2001 Apr 20;276(16):12636-44.
Angus-Hill ML, Schlichter A, Roberts D, Erdjument-Bromage H,
Tempst P, Cairns BR.
A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler
RSC in gene expression and cell cycle control.
Mol Cell. 2001 Apr;7(4):741-51.
Cairns BR, Schlichter A, Erdjument-Bromage H, Tempst P, Kornberg RD, Winston F.
Two functionally distinct forms of the RSC nucleosome-remodeling
complex, containing essential AT hook, BAH, and bromodomains.
Mol Cell. 1999 Nov;4(5):715-23.
Neely KE, Hassan AH, Wallberg AE, Steger DJ, Cairns BR, Wright
AP,
Workman JL.
Activation domain-mediated targeting of the SWI/SNF complex to
promoters stimulates transcription from nucleosome arrays.
Mol Cell. 1999 Oct;4(4):649-55.
Whitehouse I, Flaus A, Cairns BR, White MF, Workman JL, Owen-Hughes
T.
Nucleosome mobilization catalysed by the yeast SWI/SNF complex.
Nature. 1999 Aug 19;400(6746):784-7.
Cairns BR, Erdjument-Bromage H, Tempst P, Winston F, Kornberg
RD.
Two actin-related proteins are shared functional components of
the chromatin-remodeling complexes RSC and SWI/SNF.
Mol Cell. 1998 Nov;2(5):639-51.
Lorch Y, Cairns BR, Zhang M, Kornberg RD.
Activated RSC-nucleosome complex and persistently altered form
of the nucleosome.
Cell. 1998 Jul 10;94(1):29-34.
Cairns BR.
Chromatin remodeling machines: similar motors, ulterior motives.
Trends Biochem Sci. 1998 Jan;23(1):20-5. Review.
to
view PDF files, get Adobe
Acrobat Reader
|
|
