Researchers at HCI have identified and characterized mutated forms of the gene that encodes BCR-ABL, the unregulated enzyme driving the blood cancer chronic myeloid leukemia (CML).
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A team of physician-researchers from Huntsman Cancer Institute (HCI) at the University of Utah (U of U) will receive nearly $3.6 million over the next five years in a cooperative agreement with the National Institutes of Health (NIH) to establish a Network Lead Academic Participating Site (NLAPS). The award places HCI in an elite group of only 30 to 40 NLAPS locations nationwide; these sites are part of the NIH effort to create a new National Clinical Trials Network (NCTN).
Huntsman Cancer Foundation President and CEO, David Huntsman, announced today that the Jon M. Huntsman family and Huntsman Cancer Foundation have made another gift in the amount of $5,000,000 to seed the establishment of a Center of Excellence in Women’s Cancers at Huntsman Cancer Institute (HCI). In announcing the gift, Mr. Huntsman stated, “We understand the importance of striking an appropriate balance between investing in buildings and equipment, and also investing in programs and people at Huntsman Cancer Institute. This gift will support the recruitment of top talent in the cancer field to speed discovery from bench to bedside to benefit mothers, wives, sisters, and daughters.”
Only 15% of patients with squamous cell lung cancer – the second most common lung cancer – survive five years past diagnosis. Little is understood about how the deadly disease arises, preventing development of targeted therapies that could serve as a second line of defense once standard chemotherapy regimens fail.
Construction begins on the new Primary Children’s and Families’ Cancer Research Center at Huntsman Cancer Institute (HCI) at 11 a.m., Friday, June 6, when cancer survivors and friends join HCI founders Jon M. and Karen Huntsman for the official groundbreaking ceremony.
Four new genes have been added to the growing list of those known to cause increased breast cancer risk when mutated through the efforts of researchers at Huntsman Cancer Institute (HCI) at the University of Utah, who lead an international consortium working to find more gene mutations that cause inherited breast cancer susceptibilities.
Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate (GFR) — a key measure of reduced kidney function and chronic kidney disease (CKD) — is an independent risk factor for renal and urothelial cancer but not other cancer types.
In the body, a skin cell will always be skin, and a heart cell will always be heart. But in the first hours of life, cells in the nascent embryo become totipotent: they have the incredible flexibility to mature into skin, heart, gut, or any type of cell.
A Worldwide Search for the Genetic Roots of Sarcoma: Utah Researchers Awarded $250,000 International Study Grant
Two physician-researchers from Huntsman Cancer Institute (HCI) at the University of Utah will be among the principal investigators (PIs) in a new worldwide study focused on the genetics of sarcoma.
Two internationally known scholars, one in the field of cancer prevention and the other in the field of molecular biology, will join Huntsman Cancer Institute (HCI) at the University of Utah as early as September 1.
About 6 percent of colorectal cancers are diagnosed within three to five years after the patient receives a clean colonoscopy report, according to new study.
A national poll from the University of Utah's Huntsman Cancer Institute shows 34 percent of respondents would not seek genetic testing to predict their likelihood of developing a hereditary cancer - even if the cost of the testing was not an issue.
Researchers from HCI discovered a cellular mechanism that drives the spread of breast cancer to other parts of the body (metastasis), as well as a therapy which blocks that mechanism.
The Renegades of Cell Biology: Researchers Discover Why K-Ras Gene Mutations Prove So Deadly in Cancer
Cells with a mutation in the gene called K-Ras—found in close to 30% of all cancers, but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung cancer—behave in ways that subvert the normal mechanisms of cell death, according to a cell-culture study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah.
For the past ten years, clinicians throughout the United States have been performing unnecessary Pap tests for cervical cancer screening in certain groups of women, according to a researcher from Huntsman Cancer Institute (HCI) at the University of Utah.
At a time when the incidence and prevalence of cancers in all age groups—including children—is increasing, and funding for cancer research is on the decline, officials at Huntsman Cancer Institute at the University of Utah today announced a plan to expand HCI’s research capabilities—a new, 220,000-square-foot addition.
For people with a family history of adenomas, up to 10 percent of colorectal cancers could be missed when current national screening guidelines are followed.
CureSearch for Children's Cancer this week awarded researchers at Huntsman Cancer Institute at the University of Utah a $1.73 million grant to test a novel targeted treatment for Ewing sarcoma that hopefully will disrupt the cancer's growth and spread. If successful, their work could lead to new treatment for the more than 250 children diagnosed with this rare cancer each year.
The National Cancer Institute (NCI) has awarded Huntsman Cancer Institute investigator Matt VanBrocklin, Ph.D., more than $1.5 million over the next five years to continue studying the role of a gene called c-KIT in the origin and growth of melanoma, a devastating and sometimes deadly skin cancer. VanBrocklin is an assistant professor in the Department of Surgery at the University of Utah.
When a child is diagnosed with cancer, one of the first questions the parents ask is "Will my other children get cancer?" A new study from Huntsman Cancer Institute (HCI) at the University of Utah suggests the answer to that question depends on whether or not a family history of cancer exists. The research results were published online in the International Journal of Cancer and will appear in the November 15 print issue.
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