Huntsman Cancer Institute (HCI) is a leader in the study of cancer genetics and its researchers have discovered more inherited cancer genes than any other cancer center in the world. Genes responsible for breast and ovarian cancer, colon cancer, head and neck cancer, and melanoma were identified here.

From its beginning, HCI has followed a “lab bench to patient bedside” research model. HCI is the only cancer center in the region that conducts basic, translational, and clinical research simultaneously, taking what’s learned in the laboratory through drug development and into the clinic.

Recent News

New Huntsman Cancer Institute Program Personalizes Lifelong Patient Care

Huntsman Cancer Institute (HCI) at the University of Utah is launching a unique program, called HCI-Total Cancer Care, which will follow patients through cancer screenings, treatments, and into good health throughout their lives. The program, which is borne out of HCI’s membership in the Oncology Research Information Exchange Network (ORIEN), utilizes patient data to help match patients to clinical trials and treatment developments happening across the country, offering never-before-seen access to cutting edge innovations in cancer care, while tracking a patient’s health throughout his or her lifetime.

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Body Fatness and Cancer — Viewpoint of the IARC Working Group

In April 2016, the International Agency for Research on Cancer (IARC), based in Lyon, France, convened a working group to reassess the preventive effects of weight control on cancer risk. (The members of the working group for volume 16 of the IARC Handbooks are listed at the end of the article; affiliations are provided in the Supplementary Appendix, available with the full text of this article at NEJM.org.) Overweight and obesity are the abnormal or excessive accumulation of body fat that present a risk to health. The body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) is a good proxy for assessing overall body fatness. Among adults, overweight is defined as a BMI of 25.0 to 29.9 and obesity as a BMI of 30 or more.1 Obesity can further be divided into class 1 (BMI, 30.0 to 34.9), class 2 (BMI, 35.0 to 39.9), and class 3 (BMI, ≥40.0) (Table 1TABLE 1 Definitions of Classes of Overweight and Obesity. ). Worldwide, an estimated 640 million adults in 2014 (an increase by a factor of 6 since 1975) and 110 million children and adolescents in 2013 (an increase by a factor of 2 since 1980) were obese. The estimated age-standardized prevalence of obesity in 2014 was 10.8% among men, 14.9% among women,2 and 5.0% among children,3 and globally more people are overweight or obese than are underweight.

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