Nikolaus S. Trede, MD, PhD
Associate Professor, Department of Pediatrics
Nikolaus Trede, MD, PhD, is an investigator at Huntsman Cancer Institute, associate professor in the Department of Pediatrics at the University of Utah School of Medicine, and a member of the Nuclear Control of Cell Growth and Differentiation Program.
He leads a research team that investigates zebrafish to find the genetic cause of abnormal proliferations of T cells (T-ALL). T cells normally fight infection and reject foreign tissue but proliferate in one type of leukemia. With these studies, Trede and the researchers in his lab intend to uncover genes that, when mutated, can lead to leukemia in humans; these genes could then be targets for novel leukemia therapies. In addition, the Trede lab has taken a novel approach using transgenic zebrafish to discover new treatments for human T cell leukemia.
A pediatric hematologist/oncologist with an appointment at Primary Children's Medical Center, Trede also sees patients in the outpatient hematology-oncology clinic. He is also the director of Huntsman Cancer Institute's Summer Internship Program, which offers research opportunities for university-level undergraduates interested in science or medical careers.
Trede received his MD from Albert Ludwigs University Medical School in Freiburg, Germany, followed by a Diplôme d'Études Approfondies from the Institut Pasteur and a PhD from Université Paris VII, both in Paris. He completed research, clinical, and postdoctoral fellowships in immunology and hematology/oncology at Children's Hospital Boston. In 1994, Trede received a Resident Scientist Award from the National Institutes of Health. He has also received fellowships from the Leukemia Research Foundation (1997) and the Irvington Institute of Immunologic Research (1998). In 2000, the National Heart, Lung, and Blood Institute presented Trede with a Mentored Clinical Scientist Development (K08) Award.