All Grossman Lab publications can be requested as originally published pdf files by email ( This e-mail address is being protected from spambots. You need JavaScript enabled to view it )

2011

• Jenkins NC, Liu T, Cassidy P, Leachman SA, Boucher KM, Goodson AG, Samadashwily G, Grossman D: The p16 INK4A tumor suppressor regulates cellular oxidative stress. Oncogene 30:265-274, 2011. [PubMed] [PDF PMC3003740]

2010

• McKenzie JA , Liu T, Goodson AG, Grossman D: Survivin enhances motility of melanoma cells by supporting Akt activation and a5 integrin upregulation. Cancer Res 70:7927-7937, 2010 . [PubMed] [PDF PMC2955769]

• Goodson AG, Florell SR, Hyde M, Bowen GM, Grossman D: Comparative analysis of total body vs. dermatoscopic photographic monitoring of nevi in similar patient populations at risk for cutaneous melanoma. Dermatol Surg 36:1087-1098, 2010. [PubMed] [PDF PMC3025478]

• Goodson AG, Florell SR, Boucher KM, Grossman D: Low rates of clinical recurrence following biopsy of benign to moderately dysplastic melanocytic nevi. J Amer Acad Dermatol 62:591-596, 2010. [PubMed] [PDF PMC2886801]

2009

• Goodson AG, Cotter MA, Cassidy P, Wade M, Florell SR, Liu T, Boucher KM, Grossman D: Use of oral N -acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress: towards a novel paradigm for melanoma chemoprevention. Clin Cancer Res 15:7434-7440, 2009. [PubMed] [PDF PMC2787788]

• Goodson AG, Grossman D: Strategies for early melanoma detection: approaches to the patient with nevi (CME article). J Amer Acad Dermatol 60:719-735, 2009. [PubMed] [PDF PMC2292458]

2008

• Raj D, Liu T, Samadashwily G, Li F, Grossman D: Survivin repression by p53, Rb, and E2F2 in normal human melanocytes. Carcinogenesis 29:194-201, 2008. [PubMed] [PDF PMC2292458]

2007

• Cotter MA, Thomas J, Cassidy P, Robinette K, Jenkins N, Florell SR, Leachman SA, Samlowski WE, Grossman D: N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of UV-induced melanoma in mice. Clin Cancer Res 13:5952-5958, 2007. [PubMed] [PDF PMC2409148]

• Florell SR, Thomas J, Grossman D: Predominant formation of heavily pigmented dermal melanocytomas resembling ‘animal-type' melanomas in HGF (C57BL/6 x C3H)F1 mice following neonatal UV irradiation. J Cutan Pathol 34:667-674, 2007. [PubMed] [PDF PMC2410209]

• Cotter MA, Florell SR, Leachman SA, Grossman D: Absence of senescence-associated beta-galactosidase activity in human melanocytic nevi in vivo. J Invest Dermatol 127:2469-2471, 2007. [PubMed] [PDF PMC2292406]

• Thomas J, Liu T, Cotter MA, Florell SR, Robinette K, Hanks AN, Grossman D: Melanocyte expression of Survivin promotes development and metastasis of UV-induced melanoma in HGF transgenic mice. Cancer Res 67:5172-5178, 2007. [PubMed] [PDF PMC2292453]

• Fuller SR, Bowen GM, Tanner B, Florell SR, Grossman D: Digital dermoscopic monitoring of atypical nevi in patients at risk for melanoma. Dermatol Surg 33:1198-1206, 2007. [PubMed] [PDF PMC2292405]

2006

• Yan H,* Brouha B,* Liu T, Raj D, Biddle D, Lee RM, Grossman D : Proteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase. J Dermatol Sci 43:189-200, 2006. *Equal contribution [PubMed] [PDF PMC2292408]

• Liu T, Biddle D, Hanks AN, Brouha B, Yan H, Lee RM, Leachman SA, Grossman D : Activation of dual apoptotic pathways in human melanocytes and protection by Survivin. J Invest Dermatol 126:2247-2256, 2006. [PubMed] [PDF PMC2292407]

• Yan H,* Thomas J,* Liu T, Raj D, London N, Tandeski T, Leachman SA, Lee RM, Grossman D : Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonist. Oncogene 25:6968-6974, 2006. *Equal contribution [PubMed] [PDF PMC2292411]

• Raj D, Brash DE, Grossman D : Keratinocyte apoptosis in epidermal development and disease. J Invest Dermatol 126:243-257, 2006. [PubMed] [PDF PMC2291295]

2005

• Zheng W,* Hanks AN,* Boucher K, Florell SR, Allen SM, Alexander A, Brash DE, Grossman D: UVB-induced apoptosis drives clonal expansion during skin tumor development. Carcinogenesis 26:249-257, 2005. *Equal contribution [PubMed] [PDF]

• Florell SR, Bowen AR, Hanks AN, Murphy KJ, Grossman D: Proliferation, apoptosis, and survivin expression in a spectrum of melanocytic nevi. J Cutan Pathol 32:45-49, 2005. [PubMed] [PDF]

2004

• Bowen AR, Hanks AN, Murphy KJ, Florell SR, Grossman D: Proliferation, apoptosis, and survivin expression in keratinocytic neoplasms and hyperplasias. Am J Dermatopathol 26:177-181, 2004. [PubMed] [PDF]

• Liu T, Brouha B, Grossman D: Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells. Oncogene 23:39-48, 2004. [PubMed] [PDF]

2003

• Allen SM, Florell SR, Hanks AN, Alexander A, Diedrich MJ, Altieri DC, Grossman D: Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. Cancer Res 63:567-572, 2003. [PubMed] [PDF]

• Bowen AR, Hanks AN, Allen SM, Alexander A, Diedrich MJ, Grossman D: Apoptotic regulators and responses in melanocytic and keratinocytic cells. J Invest Dermatol 120:48-55, 2003. [PubMed] [PDF]

2002

• Diedrich MJ, Warters RL, Grossman D: Amifostine aminothiols and protection of keratinocyte apoptosis and DNA damage. J Invest Dermatol 119:707-708, 2002. [PubMed] [PDF]

2001

• Grossman D, Altieri DC: Drug resistance in melanoma: mechanisms, apoptosis and new therapeutic targets. Cancer Metastasis Rev 20:3-11, 2001. [PubMed] [PDF]

• Grossman D, Kim PJ, Blanc-Brude OP, Brash DE, Tognin S, Marchisio PC, Altieri DC: Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J Clin Invest 108:991-999, 2001. [PubMed] [PDF]

• Grossman D, Kim PJ, Schechner JS, Altieri DC: Inhibition of melanoma tumor growth in vivo by survivin targeting. Proc Natl Acad Sci USA 98:635-640, 2001. [PubMed] [PDF]