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Cell Response and Regulation

CRR Membership Directory
CRR 2010 Summer Newsletter
CRR 2010 Winter Newsletter
CRR 2011 Summer Newsletter
CRR 2011 Winter Newsletter

CRRThe Cell Response and Regulation (CRR) program conducts basic and translational research on the fundamental cellular mechanisms that are deregulated in cancer cells. This research provides new insight into cancer pathways and potential biomarkers.

The CRR program brings together scientists with shared research interests in two main thematic areas:

  • Cell turnover in cancer, including control of cell division and cell death and their dysregulation in cancer, as well as stem cell biology and how it informs us about tumor-initiating cells
  • Tumor microenvironment, particularly cellular processes that initiate, promote, and maintain cancer metastasis, as well as the role of inflammation and oxidative stress in the tumor microenvironment

Several members use animal models to characterize cell and tumor behavior in organisms. The diverse expertise in techniques and model systems offers great opportunity for synergistic projects and stimulating scientific exchange. This extends across Cancer Center Programs and is further promoted by the interface with disease focus groups.

The CRR program draws its members from many academic units on campus and provides a forum for interdepartmental communication among individuals who share a common interest in understanding the cellular basis of cancer.

The Cell Response and Regulation program currently receives approximately $6.7 million per year of direct research support from the National Institutes of Health, the American Cancer Society, and other funding agencies, with 13% coming from the National Cancer Institute. Cancer-focused articles published between 2003 and 2009 total 202, of which 31% are inter-programmatic and 11% are intra-programmatic publications.

Douglas Grossman, MD, PhD
Co-Leader

Katherine S. Ullman, PhD
Co-Leader

grossman bioullman bio
HCI, Room 5243
(801) 581-4682
(801) 585-7477 FAX
HCI, Room 5345
(801) 585-7123
(801) 587-8344 FAX

 

CRR Membership Directory 

 

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A

 

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B

 

  • Beckerle, Mary

    Department: Biology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-4485
    Research Interest: Cell adhesion, cell migration, Ewing's sarcoma

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C

 

  • Cassidy, Pamela

    Department: Medicinal Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-6268
    Research Interest: The role of selenium and selenoproteins in cancer, especially melanoma; oxidative stress and cancer

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D

  • Deininger, Michael

    Department: Medicine; Division of Hematoloy
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-6363
    Research Interest: Hematological malignancies and solid tumors, high-dose therapy and autologous stem cell transplantation

 

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E

 

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F

 

  • Factor, Rachel

    Department: Pathology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4763
    Research Interest: How breast cancer pathology relates to tumor behavior

  • Frost, Adam

    Department: Biochemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-8899
    Research Interest: Basic mechanisms of cellular physiology and to understand how malignancy changes these mechanisms

     

  • Fults, Daniel

    Department: Neurosurgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-6908
    Research Interest: Defective signaling in medulloblastoma

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G

 

  • Grossman, Douglas

    Department: Dermatology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-4682
    Research Interest: Apoptotic mechanisms underlying skin cancer development, with a focus on the apoptosis and cell cycle regulator, Survivin

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H

 

  •  Holmen, Sheri

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: 801-213-4237
    Research Interest: Identifying and validating novel molecular targets for cancer therapy

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I

 

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J

 

  • Jette, Cicely

    Department: Oncological Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-5568
    Research Interest: Using zebrafish model system to identify new therapeutic targets to restore normal cell death pathways to cancer cells

 

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K

 

  • Kadrmas, Julie

    Department: Oncological Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-4793
    Research Interest: Cell adhesion and migration in cancer

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L

 

  • Li, Dean

    Department: Medicine; Division of Cardiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-5505
    Research Interest: Signaling in angiogenesis; targeting angiogenesis in cancer

  • Lim, Carol

    Department: Pharmaceutics and Pharmaceutical Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-9711
    Research Interest: Targeting apoptotic mechanisms in cancer cells

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M

 

  • Moos, Philip

    Department: Pharmacology and Toxicology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-5952
    Research Interest: Redox dysregulation in cancer, selenoprotein function in cancer, cancer prevention

  • Murtaugh, L. Charles

    Department: Human Genetics
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-5958
    Research Interest: Pancreatic development and cancer

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O

 

  • O'Hare, Thomas

    Department: Medicine; Division of Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0256
    Research Interest: Target discovery and inhibitor development for chronic and acute leukemias; mechanism-based targeting of leukemic cells, including leukemia stem cells; design, validation, and coordination of function-first profiling for new therapeutic targets in leukemia

  • Oliver, Trudy

    Department: Oncoligical Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 213-4221
    Research Interest: Therapeutic response and resistance using mouse models of cancer; Regulation of the Mdm2/p53 tumor suppressor pathway

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P

 

  • Planelles, Vicente

    Department: Pathology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-8655
    Research Interest: Regulation of cell cycle and apoptosis signaling

  • Prchal, Josef

    Department: Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-3229
    Research Interest: Germ line and somatic mutations leading to myeloproliferative disorders

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R

 

  • Rosenblatt, Jody

    Department: Oncological Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4073
    Research Interest: Mechanisms and regulation of cell death and division, novel mechanisms for initiating tumor cell metastasis

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S

 

  • Sigman, Matthew 

    Department: Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0774
    Research Interest: Synthesis and biological evaluation of novel small molecule platforms; mechanism of action studies of the resultant hits

  • Spangrude, Gerald

    Department: Medicine; Division of Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-5544
    Research Interest: Stem cell biology

  • Stafforini, Diana

    Department: Medicine; Division of Cardiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-340
    Research Interest: Role of inflammation in cancer

  • Stanfield, Gillian

    Department: Human Genetics
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-9944
    Research Interest: Cell polarity, cell migration, and the role of proteases in cancer

  • Sundquist, Wesley

    Department: Biochemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-5402
    Research Interest: Membrane trafficking and cytokinesis

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T

 

  • Topham, Matthew

    Department: Medicine; Division of Pulmonary Medicine
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-3404
    Research Interest: Lipid signaling in cancer

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U

 

  • Ullman, Katharine

    Department: Oncological Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-7123
    Research Interest: Cell division, biomarkers and tumor suppressors in breast cancer

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V

 

  • VanBrocklin, Matthew

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: 801-213-4236
    Research Interest: Using pre-clinical models of cancer to identify and validate potential molecular components vital for tumor initiation

 

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W

 

  • Welm, Alana

    Department: Oncological Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4622
    Research Interest: Tumor inflammation and cancer, particularly breast cancer

  • Welm, Bryan

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4633
    Research Interest: Breast cancer stem cells, cancer drug screening

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Y

 

  • Yost, H. Joseph

    Department: Neurobiology and Anatomy
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-6110
    Research Interest: Extracellular matrix, tumor suppressor screens in zebrafish

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Z

 

  • Zhan, Fenghuang

    Department: Medicine; Division of Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 213-3718
    Research Interest: Define and target genes or their signaling pathways related to drug resistance and stem cell in myeloma

 

  • Zimmerman, Guy

    Department: Medicine; Division of Pulmonary Medicine
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0727
    Research Interest: Cell adhesion and inflammation; thrombosis in cancer

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