Director
Brian K. Dalley, PhD
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801-585-7192
The Microarray and Genomic Analysis (MGA) Shared Resource provides members of the Cancer Center access to the Affymetrix and Agilent Technologies microarray platforms and to an Illumina Genome Analyzer, which enables massively parallel DNA sequencing. The Resource is operated as a full-service facility that provides expertise in experimental and computational handling of all aspects of these technologies. Services available through the Resource include evaluation of nucleic acid sample quality, labeling of samples with modified nucleotides (cy dyes or biotin), microarray hybridization, microarray scanning, feature extraction and annotation of scanned images, Illumina sequencing library preparation, Illumina cluster generation, and sequencing of prepared libraries on an Illumina Genome Analyzer. MGA bioinformatics staff members are available to support data analysis and interpretation.
The technologies offered through the MGA Shared Resource support Cancer Center investigations with a diverse set of tools to measure gene, exon, or miRNA expression; SNP and DNA copy number profiling; location analysis of DNA binding proteins; DNA methylation status; and the sequencing of genomic DNA or resequencing of targeted regions of DNA. The MGA Shared Resource serves Cancer Center members from the laboratory-based scientific Programs (Nuclear Control of Cell Growth and Differentiation; Cell Response and Regulation; Imaging, Diagnostics, and Therapeutics; and Gastrointestinal Cancers).
Microarray and Genomic Analysis Governance
Director
Brian K. Dalley, PhD
HCI Senior Director Oversight
Bradley Cairns, PhD
Faculty Advisory Committee Chair
Bradley Cairns, PhD
Faculty Advisory Committee Members
Philip Moos, PhD
John Phillips, PhD
Monica Vetter, PhD
If use of this resource results in a publication, please acknowledge the Cancer Center Support Grant by using the following text: "The project described was supported by Award Number P30CA042014 from the National Cancer Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health."
